Table 4.
Association between prostate tissue Trx 1 and erythrocyte glutathione reductase (GR) activity.
| Erythrocyte glutathione reductase (GR) | |||||||
|---|---|---|---|---|---|---|---|
| T1 | T2 | T3 | Total | ||||
| n | % | n | % | n | % | ||
| Malignant Trx 1 | |||||||
| 0 | 2 | (50) | 1 | (25) | 1 | (25) | 4 |
| 1 | 0 | (0) | 3 | (42) | 4 | (57) | 7 |
| 2 | 9 | (45) | 6 | (30) | 5 | (25) | 20 |
| 3 | 3 | (21) | 6 | (42) | 5 | (35) | 14 |
| Fisher's exact test, P = 0.33 | |||||||
|
| |||||||
| Benign Trx 1 | |||||||
| 0 | 0 | (0) | 0 | (0) | 1 | (100) | 1 |
| 1 | 7 | (25) | 13 | (46) | 8 | (28) | 28 |
| 2 | 5 | (38) | 2 | (14) | 6 | (46) | 13 |
| 3 | 2 | (66) | 1 | (33) | 0 | (0) | 3 |
| Fisher's exact test, P = 0.17 | |||||||
|
| |||||||
| ΔTrx 1 | |||||||
| −2 | 1 | (50) | 0 | (0) | 1 | (50) | 2 |
| −1 | 1 | (25) | 2 | (50) | 1 | (25) | 4 |
| 0 | 6 | (42) | 4 | (28) | 4 | (28) | 14 |
| 1 | 5 | (29) | 5 | (29) | 7 | (41) | 17 |
| 2 | 1 | (14) | 5 | (71) | 1 | (14) | 7 |
| 3 | 0 | (0) | 0 | (0) | 1 | (100) | 1 |
| Total | 14 | 16 | 15 | 45 | |||
| Fisher's exact test, P = 0.62 | |||||||
ΔTrx 1: difference in Trx 1 level between malignant and benign prostate cells.
Median values of tertiles of GR activity are as follows: T1: 137.8 mol/min/mL; T2: 205.8 nmol/min/mL; T3: 383.8 nmol/min/mL.