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Single dose, ISF35 treatment related toxicities (N = 9)
| Number of events | |||||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Group 1 (1×108 ISF35 CLL) | Group 2 (3×108 ISF3 CLL) | Group 3 (1×109 ISF35 CLL) | |||||
|
|
|
|
|||||
| Grade 1 | Grade 2 | Grade 1 | Grade 2 | Grade 1 | Grade 2 | Grade 3 | |
| Fever | 3 | 3 | 2 | 1 | |||
| Arthralgia | 2 | 2 | 1 | 2 | |||
| Fatigue | 1 | 1 | 2 | ||||
| Nausea/vomiting | 2 | 1 | 3 | 1 | 3 | ||
| Headache | 1 | 1 | 1 | 3 | 1 | ||
| Anorexia | 2 | 1 | 2 | ||||
| Dyspnea | 1 | 1 | |||||
| Herpes simplex/zoster | 1 | 1 | |||||
| Dehydration | 1 | ||||||
| Hypotension | 1 | ||||||
| Rash | 1 | ||||||
| Upper respiratory tract symptoms | 1 | 2 | |||||
| Stomatitis | 1 | ||||||
