Table 1.
Top 10 highly expressed genes in CCl4-induced tumors in genetic cluster C
| Gene | Fold change vs control (log2) | ||
|---|---|---|---|
| Cirrhosis (CCl4-NT) | CCl4 tumor (CCl4-T) | DEN tumor (DEN-T) | |
| Insulin-like growth factor 2 (Igf2) | 6.97 | 9.70 | 3.06 |
| Lymphocyte antigen 6 complex, locus D (Ly6d) | 6.46 | 8.33 | 6.55 |
| Carboxypeptidase E (Cpe) | 3.77 | 8.21 | 7.68 |
| H19 fetal liver mRNA (H19) | 5.48 | 8.13 | 6.47 |
| Secretory leukocyte peptidase inhibitor (Slpi) | 3.52 | 6.92 | 6.35 |
| Keratin 20 (Krt20) | 4.70 | 6.83 | 4.41 |
| Stearoyl-Coenzyme A desaturase 2 (Scd2) | 4.86 | 6.51 | 5.65 |
| Topoisomerase (DNA) II alpha (Top2a) | 5.03 | 6.18 | 3.89 |
| Calcium and integrin binding family member 3 (Cib3) | 3.76 | 6.15 | 3.58 |
| Carbonyl reductase 3 (Cbr3) | 2.55 | 6.04 | 2.35 |
DEN-T, diethylnitrosamine-induced tumor; CCl4-NT, CCl4-induced cirrhotic tissue (non-tumor); CCl4-T, CCl4-induced tumor.