Table 1.
Mean values for each CFN inactivation of saccade gain, duration, and peak velocity before (PRE) and after (POST) CFN inactivation. Section 1 provides information for saccades ipsiversive to the inactivated CFN, section B for contraversive saccades and section C for saccades after we inactivated both CFNs are. We inactivated the CFN bilaterally three times. In section C we give separate measurements for saccades in each direction. The first column in each section identifies each inactivation in monkeys A, H, M, R, and W. The next two columns give the side and volume of the muscimol injection. In the PRE and POST columns bold numbers indicate values significantly different from normal (p ≤ 0.05). Numbers in the rightmost column under the GAIN, DURATION, and PEAK ACCELERATION sectors show the ratio POST/PRE coefficient of variation (CV). Values greater than 1 are bold and indicate more variability after CFN inactivation.
A. IPSILATERAL | |||||||||||
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GAIN | DURATION (ms) | PEAK VELOCITY (°/s) | |||||||||
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INJ | INJ SIDE | VOL (μL) | PRE | POST | POST/PRE CV | PRE | POST | POST/PRE CV | PRE | POST | POST/PRE CV |
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A6 | L | 0.5 | 1 | 1.92 | 59% | 40 | 60 | 97% | 470 | 593 | 73% |
A7 | R | 0.7 | 1.01 | 1.46 | 76% | 45 | 56 | 65% | 476 | 484 | 57% |
A8 | L | 0.7 | 1.09 | 2.31 | 95% | 45 | 78 | 113% | 501 | 544 | 120% |
H1 | L | 3.0 | 1.03 | 2.15 | 293% | 52 | 88 | 209% | 368 | 536 | 89% |
M3 | R | 1.0 | 1.10 | 2.16 | 71% | 58 | 109 | 158% | 399 | 450 | 89% |
M4 | L | 1.5 | 1.01 | 1.95 | 103% | 54 | 96 | 149% | 421 | 480 | 99% |
R1 | L | 0.7 | 1.00 | 2.23 | 350% | 45 | 57 | 81% | 448 | 670 | 130% |
R2 | L | 1.0 | 1.00 | 2.55 | 279% | 45 | 82 | 168% | 448 | 620 | 129% |
R3 | R | 1.0 | 0.95 | 2.26 | 236% | 48 | 74 | 206% | 404 | 551 | 112% |
W1 | R | 1.0 | 0.94 | 2.27 | 490% | 48 | 94 | 378% | 411 | 460 | 147% |
W5 | R | 1.0 | 0.99 | 1.45 | 420% | 43 | 74 | 250% | 435 | 380 | 121% |
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AVG | 1.01 | 2.06 | 225% | 48 | 79 | 170% | 435 | 524 | 106% |
B. CONTRALATERAL | |||||||||||
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GAIN | DURATION (ms) | PEAK VELOCITY (°/s) | |||||||||
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INJ | INJ SIDE | VOL (μL) | PRE | POST | POST/PRE CV % | PRE | POST | POST/PRE CV % | PRE | POST | POST/PRE CV % |
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A6 | L | 0.5 | 1.15 | 0.72 | 76% | 43 | 41 | 81% | 636 | 335 | 84% |
A7 | R | 0.7 | 1.09 | 0.81 | 143% | 45 | 46 | 86% | 501 | 352 | 148% |
A8 | L | 0.7 | 1.01 | 0.6 | 182% | 45 | 48 | 120% | 476 | 270 | 97% |
H1 | L | 3.0 | 1.00 | 1.13 | 1105% | 59 | 114 | 339% | 355 | 210 | 67% |
M3 | R | 1.0 | 1.01 | 0.99 | 173% | 55 | 58 | 114% | 379 | 374 | 107% |
M4 | L | 1.5 | 1.09 | 1.05 | 240% | 58 | 62 | 123% | 376 | 351 | 114% |
R1 | L | 0.7 | 0.95 | 0.51 | 324% | 48 | 36 | 83% | 404 | 249 | 116% |
R2 | L | 1.0 | 0.95 | 0.64 | 1321% | 48 | 50 | 374% | 404 | 236 | 101% |
R3 | R | 1.0 | 1.00 | 0.66 | 394% | 45 | 51 | 119% | 448 | 243 | 107% |
W1 | R | 1.0 | 1.04 | 0.49 | 983% | 46 | 79 | 205% | 411 | 236 | 118% |
W5 | R | 1.0 | 1.08 | 0.78 | 325% | 46 | 58 | 92% | 446 | 254 | 95% |
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AVG | 1.03 | 0.76 | 479% | 49 | 58 | 158% | 440 | 283 | 105% |
C. BILATERAL | |||||||||||
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GAIN | DURATION (ms) | PEAK VELOCITY (°/s) | |||||||||
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INJ | INJ SIDE | VOL (μL) | PRE | POST | POST/PRE CV % | PRE | POST | POST/PRE CV % | PRE | POST | POST/PRE CV % |
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B1 | L | 1.0 | 1.00 | 1.33 | 263% | 46 | 111 | 215% | 367 | 260 | 165% |
B1 | R | 1.0 | 1.05 | 1.73 | 368% | 59 | 122 | 179% | 413 | 278 | 109% |
M1 | L | 0.8 | 0.96 | 1.76 | 422% | 50 | 101 | 268% | 356 | 340 | 166% |
M1 | R | 0.8 | 1.03 | 2.36 | 219% | 55 | 120 | 192% | 382 | 400 | 116% |
R1 | L | 0.7 | 1.00 | 1.69 | 267% | 45 | 85 | 179% | 448 | 355 | 156% |
R1 | R | 0.7 | 0.95 | 1.96 | 508% | 48 | 87 | 313% | 404 | 395 | 176% |
AVG | 1.00 | 1.81 | 341% | 51 | 104 | 225% | 395 | 338 | 148% |