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. 2015 Aug 31;10(8):e0134946. doi: 10.1371/journal.pone.0134946

Fig 5. Correlation between the expression of the 4/2,4-di-O-sulfated DS domain recognized by antibody LKN1 and type I collagen (A) and the expression ratio of LKN1 and GD3A12 (B) in glomerular diseases, acute rejection and IF/TA.

Fig 5

In acute (vascular and interstitial) rejection, the interstitial expression of the 4/2,4-di-O-sulfated DS domain recognized by antibody LKN1 is increased, while expression of collagen type I is decreased (A). Expression of collagen type I is increased in glomerular diseases and IF/TA, which is accompanied by an increased expression of the 4/2,4-di-O-sulfated DS domain in glomerular diseases and a decreased expression of the 4/2,4-di-O-sulfated DS domain in IF/TA. The expression ratio of the 4/2,4-di-O-sulfated DS domain recognized by antibody LKN1 to the IdoA-Gal-NAc4S DS domain recognized by antibody GD3A12 is decreased in the IF/TA patients in contrast to the patients with acute rejection or glomerular diseases (B).