| Number of patients—n |
|
612 |
254 |
262 |
1128 |
| Age, years—median (range) |
|
28 (8–78) |
41 (12–79) |
38 (13–66) |
34 (8–79) |
| Gender—n (%) |
Male |
329 (53∙8) |
205 (80∙7) |
183 (69∙9) |
717 (63∙6) |
| Female |
283 (46∙2) |
49 (19∙3) |
79 (30∙1) |
411 (36∙4) |
| Ethnicity—n (%) |
Hispanic |
1 (0∙2) |
1 (0∙4) |
- |
2 (0∙2) |
| Non-Hispanic |
611 (99∙8) |
253 (99∙6) |
262 (100) |
1126 (99∙8) |
| Race—n (%) |
White |
- |
254 (100) |
2 (0∙8) |
256 (22∙7) |
| Black |
- |
- |
260 (99∙2) |
260 (23∙0) |
| Asian/Indian |
612 (100) |
- |
- |
612 (54∙3) |
| Pacific Islander |
- |
- |
- |
- |
| Native American |
- |
- |
- |
- |
| Other |
- |
- |
- |
- |
|
Screening Criteria
|
|
|
|
|
|
| AFB smear+ within 14 days—n (%) |
Yes |
612 (100) |
254 (100) |
262 (100) |
1128 (100) |
| No |
- |
- |
- |
- |
| a) Previously received >1 month of treatment for a prior TB episode—n (%) |
Yes |
526 (86∙0) |
59 (23∙2) |
254 (97∙0) |
839 (74∙4) |
| No |
38 (6∙2) |
192 (75∙6) |
8 (3∙0) |
238 (21∙1) |
| Unknown |
48 (7∙8) |
3 (1∙2) |
- |
51 (4∙5) |
| b) Failing standard TB treatment—n (%) |
Yes |
487 (79∙6) |
16 (6∙3) |
25 (9∙5) |
528 (46∙8) |
| No |
112 (18∙3) |
236 (92∙9) |
234 (89∙3) |
582 (51∙6) |
| Unknown |
13 (2∙1) |
2 (0∙8) |
3 (1∙2) |
18 (1∙6) |
| c) Close contact with known drug-resistant TB case—n (%) |
Yes |
169 (27∙6) |
197 (77∙5) |
29 (11∙1) |
395 (35∙0) |
| No |
208 (34∙0) |
51 (20∙1) |
167 (63∙7) |
426 (37∙8) |
| Unknown |
235 (38∙4) |
6 (2∙4) |
66 (25∙2) |
307 (27∙2) |
| d) Diagnosis with MDR-TB within last 30 days—n (%) |
Yes |
141 (23∙0) |
70 (27∙6) |
26 (9∙9) |
237 (21∙0) |
| No |
398 (65∙0) |
184 (72∙4) |
236 (90∙1) |
818 (72∙5) |
| Unknown |
73 (12∙0) |
- |
- |
73 (6∙5) |
| e) Previously diagnosed with MDR-TB and are failing TB treatment |
Yes |
240 (39∙2) |
9 (3∙5) |
- |
249 (22∙1) |
| No |
179 (29∙2) |
245 (96∙5) |
262 (100) |
686 (60∙8) |
| Unknown |
193 (31∙5) |
- |
- |
193 (17∙1) |
|
Patient Characteristics
|
|
|
|
|
|
| Previous treatment for TB—n (%) |
Yes |
312 (51∙0) |
60 (23∙6) |
248 (94∙6) |
620 (55∙0) |
| No |
156 (25∙5) |
193 (76∙0) |
13 (5∙0) |
362 (32∙1) |
| Unknown |
144 (23∙5) |
1 (0∙4) |
1 (0∙4) |
146 (12∙9) |
| If yes, number of prior TB episodes—mean, median (range) |
|
1∙1,1 (0–5) |
1∙4,1 (1–4) |
2∙3,2 (0–10) |
1∙6,2 (0–10) |
| Body Mass Index (BMI)–mean, median (range) |
|
17∙9,17∙5 (9∙0–32∙9) |
20∙4,19∙9 (12∙0–37∙2) |
18∙4,17∙9 (7∙0–32∙4) |
18∙6,18∙3 (7∙0–37∙2) |
| HIV Status—n (%) |
Positive |
14 (2∙3) |
2 (0∙8) |
141 (53∙8) |
157 (13∙9) |
| Negative |
310 (50∙6) |
252 (99∙2) |
105 (40∙1) |
667 (59∙1) |
| Unavailable |
288 (47∙1) |
- |
16 (6∙1) |
304 (27∙0) |
|
Laboratory Results
|
|
|
|
|
|
| Standardized Results—n (%) |
Smear + |
511 (83∙5) |
171 (67∙3) |
144 (55∙0) |
826 (73∙2) |
| Culture Positive |
492 (80∙4) |
226 (89∙0) |
196 (74∙8) |
914 (81∙0) |
| Standardized DST—n (%) |
Pan Susceptible |
75 (15∙2) |
87 (38∙2) |
143 (73∙3) |
305 (33∙3) |
| Mono INHR
|
19 (3∙9) |
16 (7∙0) |
16 (8∙2) |
51 (5∙6) |
| Mono RIFR
|
2 (0∙4) |
- |
3 (1∙5) |
5 (0∙5) |
| MDR-TB |
335 (68∙1) |
102 (44∙7) |
17 (8∙7) |
454 (49∙6) |
| XDR-TB |
54 (11∙0) |
14 (6∙1) |
12 (6∙2) |
80 (8∙7) |
