TARGETS | |
---|---|
GPCRsa | Enzymesc |
FZD7 receptor | ADAM |
SMO receptor | ADAM17 |
Catalytic receptorsb | Akt (PKB) |
EGFR | Aspartyl protease |
Fas | GSK3β |
HER2 | mTOR |
TGFBR1 | PARP1 |
VEGFR2 | p70S6kinase |
PKCα | |
SGK1 | |
ULK1 |
LIGANDS | |
---|---|
β-catenin | Lapatinib |
Angiopoietin-1 | LY2157299 |
Angiopoietin-2 | Neratinib |
Cisplatin | Olaparib |
Erlotinib | Rapamycin |
Everolimus | Rucaparib |
Gefitinib | Temsirolimus |
IFN-γ | TGFβ |
IGF-1 | TNF-α |
IL-1α | Veliparib |
IL-1β | Wnt |
IL-2 |
These Tables list key protein targets and ligands in this article which are hyperlinked to corresponding entries in http://www.guidetopharmacology.org, the common portal for data from the IUPHAR/BPS Guide to PHARMACOLOGY (Pawson et al., 2014) and are permanently archived in the Concise Guide to PHARMACOLOGY 2013/14
Alexander et al., 2013a,b,c,,).