Table 6. Overlapping QTLs for AIP and leukocyte subtypes with distances between peaks below 10 Mbp.
Cells/QTL (bold) | Phenotype | Chr | Peak (Mbp) | CI (Mbp) | -log10(p) |
---|---|---|---|---|---|
AIP s1 | AIP | 2 | 59.9 | 56.4–73.3 | 4.23 |
T regulatory cells | FoxP3+/CD4+ | 2 | 59.9 | 56.4–73.3 | 7.05 |
T regulatory cells | FoxP3+/CD8+ | 2 | 59.9 | 56.4–61.6 | 6.34 |
Cytotoxic T cells | CD8+/CD69+ | 2 | 65.0 | 65–66.8 | 6.43 |
T helper cells | CD44high/CD4+ | 2 | 68.1 | 59.9–71.4 | 9.62 |
Cytotoxic T cells | CD44high/CD8+ | 2 | 68.1 | 61.6–73.3 | 5.86 |
AIP s3 | AIP | 6 | 104.8 | 94–106.3 | 4.31 |
T regulatory cells | FoxP3+/CD8+ | 6 | 97.9 | 84.8–98.4 | 4.12 |
AIP s4 | AIP | 6 | 116.7 | 109.9–136.3 | 5.54 |
Th17 cells | IL17+/CD4+ | 6 | 125.0 | 125–130.2 | 4.54 |