Figure 3.
Pooled right ventricle versus pooled left ventricle Ingenuity pathway prediction: the networked differentially expressed proteins in the pooled right versus the pooled left ventricles. The 11 differentially expressed proteins used as inputs into Ingenuity are displayed with respect to expression in the left versus the right ventricles, with relative upregulation of CRYM, TPM1, CLU, TXNL1, and COQ9 in the left ventricles (red) and relative downregulation of TNNI3, SAA1, ERP29, ACTN2, HSPB2, and NDUFS3 in the left ventricles (green). In addition to these 11 proteins, predicted changes included activation of TRIM63, IFNG, MB, SOAT1, MAPT, APP, and KCNA4 and inhibition of the 26s proteasome (see color code in inset).