Figure 6.

Western blotting results for contractile proteins: the protein/normalized glyceraldehyde 3-phosphate dehydrogenase (GAPDH) percentage change on the vertical axis (protein/GAPDH % change) plotted against various clinical subject comparison groups for the contractile proteins myosin heavy chain 7 (MHC), myosin light chain 3 (MLC), troponin I 3 (TNI), tropomyosin 1 alpha (TRP), alpha actinin 2 (ACT), and desmin (DSM). Statistically significant differences between groups are marked by asterisks above the error bars. “Norm” refers to unused donor samples. A, There were no significant quantitative differences for any of the contractile proteins between the unused donor left ventricles (LV) and the pooled heart failure left ventricles or between the unused donor right ventricles (RV) and the pooled heat failure right ventricles. B, There were no significant quantitative differences by Western blotting between the unused donor left ventricles and the ischemic left ventricles or between the unused donor right ventricles and the ischemic right ventricles. C, There were significant quantitative differences by Western blotting for MHC, MLC, TNI, and TRP between the unused donor right ventricles and the nonischemic right ventricles but no significant quantitative differences between the nonischemic right ventricles and the ischemic right ventricles. D, There were no significant differences between unused donor left ventricles and the ischemic or nonischemic left ventricles.