Table S1.
Ischemic LV (n = 6) versus ischemic RV (n = 6) proteomic results
| Cluster, protein | Gene | MW, kDa | Unique peptides |
Spectral counts |
Peptide covered, % |
LV/RV AV ratio |
P, t test |
|---|---|---|---|---|---|---|---|
| Cluster 1 | 1.41 | 0.012 | |||||
| Mu-crystallin homolog | CRYM | 34 | 1 | 1 | 3 | ||
| Cluster 2 | 1.61 | 0.051 | |||||
| Tropomyosin 1 alpha | TPM1 | 33 | 18 | 26 | 41 | ||
| Mu-crystallin homolog | CRYM | 34 | 4 | 4 | 14 | ||
| Cluster 3 | 2.04 | 0.03 | |||||
| Tropomyosin 1 alpha | TPM1 | 33 | 19 | 25 | 42 | ||
| Cluster 4 | 2.61 | 0.021 | |||||
| Thioredoxin-like protein 1 | TXNL1 | 32 | 4 | 5 | 17 | ||
| Cluster 5 | 2.75 | 0.019 | |||||
| Actinin-2 fragment | ACTN2 | 104 | 9 | 10 | 11 |
Note
Unique peptides: no. of peptides unique to the parent protein in question identified by tandem mass spectrometry; spectral counts: no. of spectral counts identified by tandem mass spectrometry; peptide covered: percentage of the entire parent peptide identified by the digested peptide fragments identified by tandem mass spectrometry mapped back to the entire parent peptide. AV: average abundance; LV: left ventricle; MW: molecular weight; RV: right ventricle.