Table S4.

Paired LV (n = 4) versus RV no dysfunction (n = 4) proteomic results

						Unpaired	Paired
Cluster, protein	Gene	MW, kDa	Unique peptides	Spectral counts	Peptide covered, %	LV/RV AV ratio	P, t test	LV/RV AV ratio	P, t test
Cluster 1						NS	NS	1.37	0.011
Transferrin	TRFE	77	17	27	21
Cluster 2a						1.47	0.047	1.49	0.046
Myosin 7	MYH7	223	15	19	7
RuvB-like 2	RUVB2	51	14	19	28
Fibrin(ogen) gamma	FIBG	52	10	13	18
Cluster 3						1.47	0.036	NS	NS
Mu-crystallin homolog	CRYM	34	1	1	3
Cluster 4						1.55	0.042	NS	NS
Tropomyosin 1 alpha	TPM1	33	18	26	41
Mu-crystallin homolog	CRYM	34	4	4	14
Cluster 5b						1.36	0.048	NS	NS
WDR44	B7Z964	37	23	34	49
Desmin	DES	54	8	9	19
Cluster 6						2.68	0.014	2.61	0.024
Tropomyosin 1 alpha	TPM1	33	19	25	42
Cluster 7						1.42	0.018	1.41	0.0012
Ubiquinone biosynthesis protein COQ9 (mitochondrial)	COQ9	36	8	9	22
Cluster 8c						NS	NS	1.77	0.0067
Troponin I	TNNI3	24	7	10	28
Serum amyloid P-component	SAMP	25	6	10	26

^NoteUnique peptides: no. of peptides unique to the parent protein in question identified by tandem mass spectrometry; spectral counts: no. of spectral counts identified by tandem mass spectrometry; peptide covered: percentage of the entire parent peptide identified by the digested peptide fragments identified by tandem mass spectrometry mapped back to the entire parent peptide. AV: average abundance; LV: left ventricle; MW: molecular weight; NS: not significant; RV: right ventricle.

^aAlso weaker evidence for desmin (DES).

^bAlso weaker evidence for heme oxygenase 2 (HMOX2), lactate dehydrogenase B (LDHB), and pyruvate dehydrogenase β (PDHB).

^cAlso heat-shock protein 27 (HSP27).