Table 1.
Demographics: FREEDOM extension patients
| Characteristic | Result |
|---|---|
| Age, years | 48 ± 14 |
| Female, N (%) | 29 (76) |
| Weight, kg | |
| Female | 76 ± 24 |
| Male | 85 ± 21 |
| Etiology, N | |
| Idiopathic PAH | 26 |
| CTD-PAH | 11 |
| Background therapy (at randomization), N | None: 5, PDE5i/ERA: 22, both: 10 |
| Hemodynamics | |
| RAP, mmHg | 9 ± 6 |
| PAP, mmHg | 53 ± 15 |
| PCWP, mmHg | 9 ± 4 |
| CI, L/min/m2 | 2.5 ± 0.7 |
| SVo2, % | 61 ± 9 |
| PVR, Wood units | 11 ± 6 |
| Baseline 6MWD, median (IQR), m | 366 (314–413) |
Note
Data are reported as mean ± standard deviation unless otherwise specified. CI: cardiac index; CTD: connective-tissue disease; ERA: endothelin 1 receptor antagonist; IQR: interquartile range; PAH: pulmonary arterial hypertension; PAP: pulmonary arterial pressure; PCWP: pulmonary capillary wedge pressure; PDE5i: phosphodiesterase type 5 inhibitor; PVR: pulmonary vascular resistance; RAP: right atrial pressure; SD: standard deviation; SVo2: mixed venous oxygen saturation; 6MWD: 6-minute walk distance.