Table 2.
Baseline echocardiographic examination findings and invasive hemodynamic parameters
| Characteristic | All patients (n = 11) |
|---|---|
| Echocardiographic parameter | |
| LV end-diastolic diameter, cm | 4.2 ± 0.5 |
| LV end-systolic diameter, cm | 2.6 ± 0.5 |
| Septal wall thickness, cm | 0.9 ± 0.1 |
| Posterior wall thickness, cm | 0.9 ± 0.1 |
| LV mass index, g/m2 | 63 ± 12 |
| LV end-diastolic volume index, mL/m2 | 35.8 ± 6.0 |
| LV end-systolic volume index, mL/m2 | 13.1 ± 2.5 |
| LV ejection fraction, % | 63 ± 5 |
| Pericardial effusion, no. (%) of patients | |
| Trace | 2 (18) |
| Mild | 6 (55) |
| Moderate | 3 (27) |
| Left atrial volume index, mL/m2 | 22.1 ± 3.5 |
| E, cm/s | 78 ± 29 |
| A, cm/s | 84 ± 17 |
| E/A ratio | 1.0 ± 0.4 |
| E/e′ ratio, lateral annulus | 6.8 ± 1.9 |
| RV basal diameter,a cm | 4.9 ± 0.8 |
| RV maximal diameter,a cm | 5.8 ± 1.0 |
| RV length,a cm | 8.6 ± 1.1 |
| RV wall thickness, cm | 0.6 ± 0.1 |
| RV end-diastolic area, cm2 | 38 ± 12 |
| RV end-systolic area, cm2 | 28 ± 11 |
| Right atrial area, cm2 | 25 ± 8 |
| Ratio of RV maximal diameter to LV maximal diametera | 1.4 ± 0.3 |
| RV fractional area change, % | 29 ± 11 |
| Tricuspid annular plane systolic excursion, cm | 1.6 ± 0.5 |
| RV tissue Doppler s′ velocity, cm/s | 12.4 ± 3.0 |
| Absolute RV global longitudinal strain, % | 15.8 ± 5.2 |
| Pulmonary artery systolic pressure, mmHg | 69 ± 33 |
| Right atrial pressure, mmHg | 8 ± 4 |
| Cardiac index, L/min/m2 | 3.0 ± 0.8 |
| Invasive hemodynamic parameter | |
| Right atrial pressure, mmHg | 9.5 ± 8.5 |
| Pulmonary artery systolic pressure, mmHg | 73 ± 21 |
| Pulmonary artery diastolic pressure, mmHg | 31 ± 10 |
| Mean pulmonary arterial pressure, mmHg | 48 ± 14 |
| Pulmonary capillary wedge pressure, mmHg | 13 ± 2.5 |
| Cardiac output, L/min | 5.4 ± 1.8 |
| Cardiac index, L/min/m2 | 2.9 ± 0.9 |
| Pulmonary arterial saturation, % | 65 ± 9 |
| Pulmonary vascular resistance, Wood units | 7.4 ± 4.0 |
Note
Data are expressed as mean value (±SD) unless otherwise indicated. Baseline echocardiographic and invasive hemodynamic parameter data were measured for all 11 study participants, because all participants enrolled in the study completed baseline cardiac testing. A: late mitral inflow velocity; E: early mitral inflow velocity; e′: early diastolic mitral annular velocity; LV: left ventricle; RV: right ventricle; s′: peak systolic velocity.
a
Measured in the apical 4-chamber view