Table 2. Clinical presentation of influenza patients according to age group and influenza virus type and subtype in the age groups 0–4 years and 5–14 years.

Univariate analysis. The IBVD (Influenza B in Vircases database) study, France, 2003–2004 to 2012–2013.

	0–4 years				5–14 years
	B (a)	A (a)	A(H3N2)	A(H1N1)pdm09	B (a)	A (a)	A(H3N2)	A(H1N1)pdm09
	n = 728	n = 2711	n = 1163	n = 913	n = 1432	n = 3284	n = 1042	n = 1488
Gender ratio (M/F)	1.0	1.1	1.1	1.0	1.2	1.2	1.2	1.2
% of patients with 7 symptoms or more	22.5%	23.7%	22.5%	24.8%	47.0%	48.4%	51.1% *	45.8%
Symptoms (%) (b)
Fever	99.2%	99.0%	99.0%	99.1%	98.9%	98.6%	98.3%	98.7%
Asthenia	59.4%	60.2%	60.4%	63.8%	78.5%	77.7%	76.9%	80.2%
Myalgia	-	-	-	-	56.7%	57.4%	57.4%	57.9%
Shivering	33.8%	38.1% *	38.3%	36.4%	61.4%	63.6%	64.2%	61.5%
Cephalalgia	-	-	-	-	74.6%	74.1%	74.5%	74.4%
Cough	78.1%	79.9%	80.4%	83.5% **	82.1%	86.1% **	84.1%	89.6% **
Expectoration	9.6%	11.8%	9.5%	13.1% *	10.9%	13.4% *	11.9%	14.1% *
Bronchitis/bronchiolitis	6.0%	7.1%	7.1%	6.5%	5.6%	6.4%	6.2%	6.1%
Rhinitis	77.4%	80.9% *	83.4% **	75.4%	74.5%	72.2%	76.5%	65.7% **
Pharyngitis	49.9%	49.6%	50.6%	45.8%	55.0%	55.1%	60.9% **	48.6% **
Otitis/earache	14.4%	12.7%	12.5%	11.9%	5.6%	5.9%	7.7% *	4.3%
Gastrointestinal symptoms	20.0%	20.2%	19.7%	22.1%	24.9%	21.8% *	21.6%	21.3% *
Conjunctivitis	12.0%	13.1%	13.5%	10.0%	11.6%	11.6%	11.3%	9.8%
Adenopathy	10.7%	12.0%	11.0%	9.4%	14.7%	14.7%	15.5%	12.1%

^(a) These include all influenza cases, including those that were not subtyped/characterized.

^(b) sudden onset of symptoms is not presented as included in the ARI case definition; dyspnoea is not presented as only collected since the 2009–2010 season; myalgia and cephalalgia were not considered among children aged 0–4 years as they cannot report their subjective symptoms.

p-value for the comparison with influenza B patients of the same age group:

* <0.05

**<0.01