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. 2015 Sep 1;10(9):e0136186. doi: 10.1371/journal.pone.0136186

Table 3. Clinical presentation of influenza patients according to age group and influenza virus type and subtype in the age groups 15–64 years and 65 years or older.

Univariate analysis. The IBVD (Influenza B in Vircases database) study, France, 2003–2004 to 2012–2013.

15–64 years 65+ years
B (a) A (a) A(H3N2) A(H1N1)pdm09 B (a) A (a) A(H3N2) A(H1N1)pdm09
n = 1213 n = 4787 n = 2149 n = 1594 n = 73 n = 195 n = 129 n = 27
Gender ratio (M/F) 0.9 1 0.9 1 0.7 0.8 0.8 1.1
% of patients with 7 symptoms or more 68.4% 68.9% 71.5% 64.9% * 56.2% 53.9% 55.0% 55.6%
Symptoms (%) (b)                
Fever 96.6% 96.3% 96.5% 96.2% 97.3% 95.8% 95.3% 92.6%
Asthenia 90.0% 88.4% 88.0% 88.9% 83.6% 80.4% 78.3% 85.2%
Myalgia 89.3% 89.1% 90.0% 87.0% 84.9% 77.3% 75.2% 85.2%
Shivering 82.4% 83.7% 84.7% 80.8% 77.5% 69.4% 69.5% 70.4%
Cephalalgia 81.5% 81.8% 83.1% 78.1% * 73.6% 65.5% 66.7% 55.6%
Cough 90.0% 88.4% 87.2% * 93.1% ** 94.4% 89.2% 91.5% 88.9%
Expectoration 23.3% 24.7% 24.9% 23.1% 30.9% 31.7% 30.6% 42.3%
Bronchitis/bronchiolitis 8.9% 9.4% 10.5% 6.8% * 15.9% 16.7% 17.8% 15.4%
Rhinitis 76.4% 74.4% 77.7% 67.6% ** 69.4% 76.3% 73.6% 74.1%
Pharyngitis 67.0% 61.0% ** 62.6% * 55.1% ** 46.5% 51.8% 48.8% 40.7%
Otitis/earache 9.3% 6.7% ** 6.4% ** 6.6% ** 0.0% 3.1% 2.3% 3.7%
Gastrointestinal symptoms 15.8% 16.4% 17.1% 15.2% 17.1% 11.3% 10.1% 0.0% *
Conjunctivitis 11.5% 10.6% 11.8% 7.0% ** 4.5% 6.9% 8.3% 3.7%
Adenopathy 9.0% 10.3% 11.5% 8.0% 6.9% 4.0% 2.1% 7.4%

(a) These include all influenza cases, including those that were not subtyped/characterized.

(b) sudden onset of symptoms is not presented as included in the ARI case definition; dyspnoea is not presented as only collected since the 2009–2010 season; myalgia and cephalalgia were not considered among children aged 0–4 years as they cannot report their subjective symptoms.

p-value for the comparison with influenza B patients of the same age group:

* <0.05

**<0.01