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. 2015 Sep 1;10(9):e0136186. doi: 10.1371/journal.pone.0136186

Table 4. Clinical Presentation of Influenza B Patients According to Age Group and Virus Lineage (Victoria versus Yamagata).

The IBVD (Influenza B in Vircases database) Study, France, 2003–2004 to 2012–2013.

0–4 years 5–14 years 15–64 years >65 years
B Yamagata B Victoria B Yamagata B Victoria B Yamagata B Victoria B Yamagata B Victoria
  (n = 318) (n = 136) (n = 415) (n = 397) (n = 488) (n = 232) (n = 36) (n = 13)
Gender ratio 1.0 1.0 1.2 1.4 1.0 1.0 0.9 0.7
% of patients with 7 symptoms or more 21.4% 22.8% 41.2% 48.7% * 65.7% 64.2% 50.0% 53.9%
Symptoms (%) ( a )                
Fever 99.7% 100.0% 99.0% 98.5% 96.3% 97.0% 94.4% 100.0%
Asthenia 58.2% 64.7% 78.0% 77.6% 90.1% 88.8% 88.9% 69.2%
Myalgia 24.6% 28.7% 52.7% 57.9% 90.3% 87.5% 83.3% 92.3%
Shivering 31.8% 33.1% 59.6% 64.8% 83.2% 78.3% 80.6% 61.5%
Cephalalgia 26.2% 34.6% 71.7% 80.6% ** 79.5% 81.5% 74.3% 84.6%
Cough 80.3% 82.4% 81.1% 84.9% 88.8% 90.1% 97.1% 92.3%
Expectoration 6.8% 12.5% * 10.0% 12.9% 23.3% 17.3% 32.4% 38.5%
Bronchitis/bronchiolitis 3.2% 4.4% 3.0% 4.3% 8.5% 6.1% 17.6% 23.1%
Rhinitis 77.5% 75.7% 65.9% 77.3% ** 76.0% 75.8% 71.4% 61.5%
Pharyngitis 54.1% 52.9% 52.4% 61.5% ** 65.0% 71.2% 37.1% 61.5%
Otitis/earache 14.7% 11.8% 6.5% 5.3% 9.9% 5.2% * 0.0% 0.0%
Gastrointestinal symptoms 19.9% 11.0% * 24.0% 21.4% 14.5% 17.2% 18.2% 15.4%
Conjunctivitis 10.6% 12.1% 8.1% 12.0% 11.1% 10.8% 0.0% 16.7% *
Adenopathy 10.6% 12.1% 15.1% 12.7% 7.0% 10.3% 4.0% 0.0%

a Sudden onset of symptoms is not presented as included in the ARI case definition; dyspnoea is not presented as only collected since the 2009–2010 season.

p-value for the comparison with influenza B patients of the same age group:

* <0.05

**<0.01