. Author manuscript; available in PMC: 2016 Mar 1.

Published in final edited form as: Kidney Int. 2015 Apr 1;88(3):576–583. doi: 10.1038/ki.2015.104

Table 7. Area under the ROC Curve and NRI for Pre-operative and First Post-Operative Log(H-FABP).

Pre-operative log(H-FABP)	Any AKI	Severe AKI	Mortality
Area Under ROC (95% CI)
clinical model¹	0.69 (0.66, 0.73)	0.76 (0.68, 0.83)	0.74 (0.64, 0.80)
Log(H-FABP)+clinical model	0.71 (0.67, 0.74)	0.78 (0.70, 0.86)	0.75 (0.68, 0.83)
Continuous NRI
Overall NRI (95% CI)	0.32 (0.19, 0.46)	0.36 (0.02, 0.70)	0.54 (0.21, 0.87)
NRI for events	0.16	0.06	0.00
NRI for non-events	0.16	0.30	0.54

First Post-operative log(H-FABP)

Area Under ROC (95% CI)
clinical model²	0.71 (0.67, 0.74)	0.79 (0.72, 0.86)	0.73 (0.64, 0.80)
Log(H-FABP)+clinical model	0.72 (0.69, 0.76)	0.84 (0.77, 0.92)	0.74 (0.66, 0.81)
Continuous NRI
Overall NRI (95% CI)	0.24 (0.11, 0.36)	0.87 (0.57, 1.17)	0.39 (0.07, 0.71)
NRI for events	-0.23	0.41	0.03
NRI for non-events	0.47	0.46	0.36

Clinical model included age (per year), sex, white race, non-elective surgery, diabetes, hypertension, center, congestive heart failure, myocardial infarction, pre-operative urine albumin to creatinine ratio, and type of surgery (CABG or valve versus all others)

Clinical model included for age (per year), sex, white race, cardiopulmonary bypass time > 120 minutes, non-elective surgery, pre-operative estimated GFR, diabetes, hypertension, center, congestive heart failure, myocardial infarction, pre-operative urine albumin to creatinine ratio, and type of surgery (CABG or valve versus all others).