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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: J Pain. 2015 Jun 25;16(9):913–925. doi: 10.1016/j.jpain.2015.05.013

Table 4.

Group Differences in Brain Response to Positively and Negatively Valenced Faces and Inhibitory Control in Emotional vs. Non-emotional Contexts

Peak Anatomic
Location
Regions
Included
# Voxelsa x y z t statisticb Cohen’s dc

FH+Pain vs. FH−Pain

Go

Happy > Calm

None

Happy < Calm

1. Left Fusiform Gyrus Cerebellum, PHG, MTG 162 −50 −47 −13 −2.76 1.48
2. Right Fusiform
Gyrus
LG, MOG, IOG,
Declive
97 38 −65 −10 −2.73 1.46
3. Right IPL SMG 47 65 −35 30 −3.12 1.67
4. Right Cuneus MOG, SOG, MTG 46 32 −86 27 −2.78 1.49
5. Left Uncus Amyg, STG, PHG 44 −23 2 −25 −2.75 1.47
6. Right Culmen PHG, Fusiform
Gyrus
43 32 −35 −19 −2.79 1.49
7. Right IFG STG, PHG 39 26 14 −16 −2.83 1.51
8. Right Thalamus PHG, MB, STN 39 2 −11 −7 −2.91 1.56
9. Left Precuneus 30 −17 −74 48 −2.60 1.39
10. Right PHG Thalamus, SN,
STN, MB
27 14 −23 −13 −2.78 1.49

Go

Scared > Calm

None

Scared < Calm

1. Left SFG MFG 41 −17 71 6 −2.83 1.51
2. Left PCC PHG, LG, Culmen 35 −5 −50 6 −3.09 1.65
3. Right Precuneus 35 26 −68 33 −2.81 1.50
4. Right Declive 34 2 −80 −22 −2.61 1.40
5. Right SFG MFG, MeFG 33 20 8 54 −2.85 1.52

Calm NoGo

Happy > Calm

None

Happy < Calm

1. Right Postcentral IPL, Cingulate
Gyrus Gyrus, Precentral
Gyrus
150 35 −35 63 −2.58 1.38
2. Right IFG Insula, STG 80 47 14 −1 −2.50 1.34

Calm NoGo

Scared > Calm

1. Right MTG PCC, Cuneus,
Precuneus
26 −29 −68 30 3.01 1.61
2. Right Cingulate
Gyrus
PCC 25 5 −29 27 2.62 1.40

Scared < Calm

None

PHG = parahippocampal gyrus, MTG = middle temporal gyrus, LG = lingual gyrus, MOG = middle occipital gyrus, IOG = inferior occipital gyrus, SMG = supramarginal gyrus, SOG = superior occipital gyrus, STG = superior temporal gyrus, MB = mammillary body, STN = subthalamic nucleus, SN = substantia nigra, MFG = middle frontal gyrus, MeFG = medial frontal gyrus, IPL = inferior parietal lobule, PCC = posterior cingulate cortex, IFG = inferior frontal gyrus, SFG = superior frontal gyrus

a

Voxel sizes were determined by examining voxel count reports of the voxel/cluster thresholded maps using Analysis of Functional NeuroImage’s (AFNI’s) Graphic User Interface cluster report tool.

b

t values of the clusters were determined by extracting t-values using AFNI’s 3dROIstats tool from the corresponding t statistical sub-brick of the resulting voxel/cluster thresholded maps.

c

Cohen’s d for independent samples t-tests was calculated using the following formula: Cohen’s d = 2t/√df (Rosenthal & Rosnow, 1991). All of the effect sizes reported are considered large (Cohen’s d > 0.8).