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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Int Immunopharmacol. 2015 Jun 25;28(1):359–368. doi: 10.1016/j.intimp.2015.06.018

Fig. 7.

Fig. 7

Chronic alcohol consumption increases IL-4-producing iNKT cells in melanoma-bearing mice. PBL from tumor-bearing mice were isolated three weeks after tumor inoculation and stimulated with αGalCer for 4 hr. IL-4 and IFN-γ-producing iNKT cells were analyzed by flow cytometry. A. Percentage of IL-4 and IFN-γ-producing iNKT cells in the blood iNKT cells. B. Ratio IL-4-producing iNKT cells to IFN-γ-producing iNKT cells in the blood of water-drinking mice and alcohol-consuming mice. Each group contained 6-10 mice. Each experiment was repeated twice with similar results. Values are mean± SD. Two tailed Student's t-test was used to analyze the difference between groups. *Different from Water, p<0.05; **Different from Water, p<0.01; ***Different from Water, p<0.001. Water=water-drinking mice. EtOH=alcohol-consuming mice.