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Hydrogel formation and in vitro characterization. Chemical structure of HeMA-HA macromer, where 25% of the HA repeat units were modified with HeMA groups (A). Representative rheological time sweep after mixing HeMA-HA macromer with APS and TEMED, where the intersection of the storage (Gprime;) and loss (G″) moduli is defined as gel onset (B). Time to complete degradation and initial mechanics of the HeMA-HA formulation used for in vivo studies, n=4 (C). Data presented as mean ± SD.
