Table 3.
Comparative Risk for Outcomes among Different Hypertension Categories
| Outcome (Mean follow up) | Ischemic Heart Event (4.20) | Congestive Heart Failure (4.28) | Cerebrovascular Event (4.26) | End Stage Renal Disease (4.25) | Mortality (4.33) | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Crude HR (95% CI) | Adjusted HR (95% CI) | Crude HR (95% CI) | Adjusted HR (95% CI) | Crude HR (95% CI) | Adjusted HR (95% CI) | Crude HR (95% CI) | Adjusted HR (95% CI) | Crude HR (95% CI) | Adjusted HR (95% CI) | |
| RH (cRH+uRH) vs non-RH | 1.98 (1.92, 2.03) | 1.24 (1.20,1.28) | 3.36 (3.23, 3.49) | 1.46 (1.40, 1.52) | 1.81 (1.74, 1.88) | 1.14 (1.10, 1.19) | 2.94 (2.84, 3.04) | 1.32 (1.27, 1.37) | 1.80 (1.76, 1.85) | 1.06 (1.03, 1.08) |
| cRH vs non-RH | 2.33 (2.23, 2.42) | 1.21 (1.16, 1.26) | 4.37 (4.16, 4.59) | 1.51 (1.43, 1.59) | 1.80 (1.70, 1.90) | 1.01 (0.95, 1.07) | 3.26 (3.11, 3.43) | 1.16 (1.10, 1.22) | 2.13 (2.06, 2.20) | 1.05 (1.02, 1.09) |
| uRH vs non-RH | 1.77 (1.70, 1.83) | 1.26 (1.21, 1.31) | 2.74 (2.61, 2.89) | 1.42 (1.35, 1.50) | 1.81 (1.73, 1.90) | 1.24 (1.18, 1.30) | 2.74 (2.62, 2.86) | 1.45 (1.39, 1.52) | 1.60 (1.55, 1.65) | 1.06 (1.03, 1.09) |
| cRH vs uRH | 1.32 (1.25, 1.39) | 0.96 (0.91, 1.01) | 1.59 (1.49, 1.69) | 1.06 (0.99, 1.12) | 0.99 (0.93, 1.06) | 0.81 (0.76, 0.88) | 1.19 (0.99, 1.27) | 0.80 (0.75, 0.85) | 1.33 (1.28, 1.39) | 0.99 (0.95, 1.03) |
*
Models were adjusted for age, race, gender, BMI, eGFR, Charlson Comorbidity Index, and co-morbidities including CKD and DM
RH(resistant hypertension); cRH (BP<140/90 on 4 or more medicine); uRH (SBP>/=140/90 on 3 or more medicines)
SBP (systolic blood pressure); DBP (diastolic blood pressure); BMI (Body mass index)