Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas

. Author manuscript; available in PMC: 2016 Sep 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Jul 17;1849(9):1179–1187. doi: 10.1016/j.bbagrm.2015.07.010

Figure 9. Quantification of BRCA1 mRNA levels by qPCR in the CDK12as cell line following addition of 10 μM 1-NM-PP1. Expression values are standardized to the 0 hr timpoint (before addition of inhibitor) whose value was set at 1, error bars are +/−1 standard errors of the mean, n=3.