Table 3. Molecular properties of the gap junction inhibitors (rows 2–4) as compared to the properties identified by Tice [33] for screening for novel insecticides (row 5).

Inhibitor	Molecular Weight	cLog P	Hydrogen Bond Donors	Hydrogen Bond Acceptors	Rotatable Bonds
Carbenoxolone	570.77	4.83	0	7	6
Mefloquine	378.32	3.70	2	3	4
Meclofenamic Acid	296.15	4.92	2	3	3
Tice Rule of 5	< 500	< 5	0	< 10	< 12