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. 2015 Sep 1;11(9):e1005135. doi: 10.1371/journal.ppat.1005135

Fig 3. KSHV latency locus confers hyper-responsiveness to LPS in the environment of forced Myc overexpression.

Fig 3

Proliferation was evaluated by incorporation of 5-ethynyl-2'-deoxyuridine (EdU) into DNA. Splenic B cells from the transgenic (n = 5) and wild-type mice (n = 5) were cultured with varying doses of LPS (A), or anti-IgM (B), or anti-CD40 antibody (C), or loxoribine (D), or CpG (E), or non-CpG (F) for 72 hours. Relative fluorescence unit (RFU) was measured and is expressed as ex vivo cell proliferation.