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. 2015 Sep 1;11(9):e1005148. doi: 10.1371/journal.ppat.1005148

Fig 2. Protection of Balb/c mice from VACVWR by anti-A33 mAbs.

Fig 2

Antibody protection against weight loss (A) and mortality (B) caused by VACVWR challenge. All analyzed anti-A33 MAbs protect both against weight loss and death. One of two independent experiments is shown. Significance for all A33 antibodies (****) was P<0.0001, while the anti-L1 control antibody M12B9 was not significant (ns) with P = 0.1577. The negative control antibody A10 provided no protection as expected, while the positive control anti-B5 antibody B126 conferred protection. (B) Note that slight shifts on the Y-axis were implemented for visualization purposes for all antibodies that confer full protection.