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. 2015 Sep 1;9(9):e0004052. doi: 10.1371/journal.pntd.0004052

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© 2015 Sim et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 6 — Circos plot [26] of mutational hot- and coldspots detected in human- and mosquito-derived DENV2 populations. Red, hotspots in human-derived populations; orange, hotspots in mosquito-derived populations; each hotspot was found in a single population. Purple, coldspots indicating a depletion of SNVs across all 46 mosquito-derived populations. No coldspots were detected in human-derived populations.