Table 2. Distribution of diagnosis and neural cell adhesion molecule (NCAM) interstitial positivity (including the number of NCAM positive interstitial cells presented with mean ±SD) observed among stages of interstitial renal fibrosis (IRF).
Diagnosis | IRF-0 | IRF-1 | IRF-2 | IRF-3 | ||||
---|---|---|---|---|---|---|---|---|
Total N (NCAM+ cases) | mean*±SD | Total N (NCAM+ cases) | mean*±SD | Total N (NCAM+ cases) | mean*±SD | Total N (NCAM+ cases) | mean*±SD | |
FSGS | 6 (3/6) | 0.8±1.2 | 11 (8/11) | 3.6±3.6 | 1 (0/1) | 0.0±NA | - | - |
Kidney graft | - | - | 3 (2/3) | 3.0±3.0 | 1 (1/1) | 2.0±NA | 5 (0/5) | 0.0±0.0 |
MGN | 7 (4/7) | 1.0±1.2 | 4 (4/4) | 6.5±4.4 | - | - | 2 (1/2) | 1.5±2.1 |
Lupus nephritis | 5 (2/5) | 0.6±0.9 | 13 (12/13) | 5.3±3.3 | 6 (4/6) | 3.5±3.8 | 1 (1/1) | 1.0±NA |
MesPGN | 1 (1/1) | 2.0±NA | 4 (4/4) | 3.8±1.7 | - | - | - | - |
MPGN | 2 (1/2) | 0.5±0.71 | 3 (3/3) | 3.7±2.1 | 3 (1/3) | 1.7±2.9 | - | - |
Minimal changes | 4 (0/4) | 0.0±0.0 | - | - | - | - | - | - |
IgA nephropathy | 4 (2/4) | 0.5±0.6 | 1 (1/1) | 4.0±NA | 1 (0/1) | 0.0±NA | - | - |
RPGN | - | - | - | - | 1 (0/1) | 0.0±NA | 4 (3/4) | 0.8±0.5 |
Statistical analysis | - | p = 0.527 # | - | p = 0.657 # | - | p = 0.831 # | - | p = 0.137 ## |
N- number of cases;
*- mean number of NCAM+ cells per field of view x400;
NA- not applicable;
#- ANOVA test was applied;
##- Kruskall-Wallis test was applied because Levene’s test of homogeneity of variances was <0.050 and consequently ANOVA could not be used.