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Expression of IL-6, TNF, IFN-γ and IL-12p70 in tumor bearing mice treated daily with 1 nmol (A,B) or 2 nmol (C) CpG/CpG-siRNA conjugates 7 (A) or 4 days (B,C) after tumor challenge. Mean cytokines serum levels in fg/ml measured by CBA; * indicates p<0.05, ** indicates p<0.01, *** indicates p<0.001 compared to CpG treated cells.
