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. 2015 Aug 14;6:287–296. doi: 10.1016/j.redox.2015.08.012

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© 2015 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 4 — Anti-inflammatory properties of sulindac and NOSH-sulindac. Rat paw edema was induced by carrageenan injection as described in Section 2.9. SUL and NOSH-SUL were both equally effective in reducing paw volume at all time points (panel A). Results are mean±SEM of 5 rats in each group, ^†P<0.05 vs vehicle treated rats at all time points. SUL and NOSH-SUL also caused a significant reduction in PGE₂ levels in the paw exudate (panel B). Results are mean±SEM for 5 rats in each group, ^†P<0.01 vs vehicle, *P <0.05 vs NOSH-SUL.