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TFEB expression attenuates Aβ generation, in vitro. A, B, Abundance of Aβ40 and Aβ42 species in the cell lysates (A) and medium (B) in N2a-APP695 cells transfected with TFEB or vector control. C, D, Accumulation of Aβ40 (C) and Aβ42 (D) species in the overlying medium of cells treated as in A, over the indicated duration. N = 5 per group; *p < 0.05, **p < 0.01.
