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DNA damage repair system mutants have reduced survival after ofloxacin treatment in stationary phase. Ofloxacin persisters decreased approximately 104-fold in ΔrecA mutants, 103-fold in ΔrecB mutants, and 50-fold in ΔruvA and ΔrecN mutants. ΔrecF, ΔtisAB, and ΔdksA resulted in persister levels comparable to those of the WT. Data are average values ± standard errors from at least three biological replicates.
