Table 3.
Multivariate analysis of risk factors associated with in-hospital death from invasive pneumococcal infection
| Univariate RR (95% CI) | Multivariate RR (95% CI)* | |
| Serotype | ||
| Other | 1.0 | 1.0 |
| Type 3 | 2.14 (1.17–3.91) | 2.54 (1.22–5.27) |
| Type 1 | 0.29 (0.11–0.77) | 0.23 (0.06–0.97) |
| Age, years | ||
| 18–49 | 1.0 | 1.0 |
| 50–65 | 2.00 (1.08–3.68) | 2.23 (1.00–4.97) |
| 65–79 | 1.74 (1.01–2.99) | 3.20 (1.50–6.81) |
| > 80 | 1.79 (1.01–3.18) | 2.86 (1.23–6.65) |
| Comorbidity** | ||
| No | 1.0 | 1.0 |
| Yes | 1.44 (0.99–2.10) | 1.24 (0.78–2.00) |
| Alcoholism | ||
| No | 1.0 | 1.0 |
| Yes | 1.55 (1.00–2.40) | 1.82 (0.97–3.42) |
| B-leukocyte count | ||
| > 9 109/L | 1.0 | 1.0 |
| ≤ 9 109/L | 2.07 (1.39–3.08) | 2.76 (1.66–4.59) |
| Temperature | ||
| ≥ 38.5°C | 1.0 | 1.0 |
| < 38.5°C | 1.79 (1.23–2.61) | 1.67 (1.07–2.62) |
*: Cox regression with all variables forced into the model. RRs are adjusted with all variables included in the model. **: includes patients with chronic lung disease, chronic heart disease, chronic renal disease, chronic liver disease, diabetes mellitus, cancer, autoimmune disease, human immunodeficiency virus (HIV) infection, and 'other chronic diseases'. Patients may have more than one comorbidity.