Table 2.
Fasting plasma cytokines and LPS- and PamCSK4-induced cytokine release from whole blood cultures before and after 2 wk of HIIT or MICT
| HIIT |
MICT |
P Value |
|||||
|---|---|---|---|---|---|---|---|
| Variable | Pre | Post | Pre | Post | Time | Group | Interaction |
| Fasting plasma cytokines, pg/ml | |||||||
| TNF-α | 12.1 (3.4) | 13.3 (4.0) | 15.5 (5.2) | 15.1 (5.4) | 0.26 | 0.11 | 0.06 |
| IL-6 | 2.6 (1.4) | 2.8 (1.9) | 2.3 (1.5) | 2.0 (1.3) | 0.76 | 0.32 | 0.23 |
| IL-1β | 1.3 (1.6) | 1.2 (1.3) | 1.0 (1.6) | 1.0 (1.6) | 0.99 | 0.54 | 0.60 |
| IL-10 | 2.4 (2.9) | 2.3 (1.8) | 7.7 (11.6) | 6.4 (11.5) | 0.16 | 0.05 | 0.05 |
| LPS-induced cytokines, pg/CD45+ leukocyte x 104 | |||||||
| TNF-α | 3.3 (3.4) | 4.2 (4.2) | 5.1 (5.3) | 7.5 (5.8) | 0.13 | 0.26 | 0.47 |
| IL-6 | 8.7 (5.9) | 8.3 (5.5) | 7.0 (7.3) | 10.0 (5.9) | 0.40 | 0.99 | 0.26 |
| IL-1β | 1.3 (1.2) | 1.5 (1.6) | 1.1 (1.4) | 2.2 (1.0) | 0.22 | 0.66 | 0.40 |
| IL-10 | 1.1 (0.4) | 1.0 (0.3) | 0.9 (0.3) | 1.2 (0.4) | 0.18 | 0.84 | 0.10 |
| PamCSK4-induced cytokines, pg/CD45+ leukocyte x 104 | |||||||
| TNF-α | 2.3 (2.9) | 2.4 (1.5) | 2.0 (1.2) | 1.4 (1.0) | 0.74 | 0.43 | 0.52 |
| IL-6 | 8.4 (5.2) | 9.6 (4.8) | 8.7 (8.1) | 6.7 (7.6) | 0.66 | 0.70 | 0.06 |
| IL-1β | 0.2 (0.1) | 0.2 (0.2) | 0.3 (0.3) | 0.8 (1.4) | 0.23 | 0.25 | 0.36 |
| IL-10 | 1.3 (0.8) | 1.1 (0.2) | 1.4 (0.6) | 1.1 (0.6) | 0.17 | 0.92 | 0.88 |
| Immune cell number, x103 per μl/blood | |||||||
| Lymphocytes | 0.57 (0.2) | 0.51 (0.2) | 0.53 (0.2) | 0.55 (0.2) | 0.26 | 0.98 | 0.08 |
| CD14+ monocytes | 0.20 (0.07) | 0.19 (0.07) | 0.15 (0.05) | 0.16 (0.05) | 0.99 | 0.08 | 0.81 |
| CD15+ neutrophils | 2.5 (1.5) | 2.1 (0.7) | 2.1 (0.9) | 1.9 (0.5) | 0.20 | 0.30 | 0.87 |
Values are means (SD). HIIT, high-intensity interval training; MICT, moderate-intensity continuous training.