Table 1.
Antibacterial activity tests of magnolol against methicillin-resistant S. aureus (MRSA).
| S. aureus strain | Class | Magnolol (μg/mL)∗ | Oxacillin 25 μg/mL + magnolol (μg/mL)∗ |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 10 | 25 | 50 | 0 | 1 | 10 | 25 | 50 | ||
| ATCC25923 | MSSA | +++ | +++ | +++ | +/− | — | — | — | — | — | — |
| ATCC33591 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | +++ | — | — |
| Clinical isolates | |||||||||||
| S. aureus 78 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | — | — | — |
| S. aureus M11 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — |
| S. aureus 21-8 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | +/− | — | — |
| S. aureus 6-2 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | — | — | — |
| S. aureus 7-3 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — |
| S. aureus 8-4-1 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — |
| S. aureus 8-4-2 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — |
| S. aureus 9-5 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — |
| S. aureus 13-7 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | +/− | — | — |
| S. aureus 27-9 | MRSA | +++ | +++ | +++ | — | — | +++ | +++ | — | — | — |
| S. aureus 47-10 | MRSA | +++ | +++ | +++ | — | — | +/− | +/− | — | — | — |
| S. aureus 105-13 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | — | — | — |
| S. aureus 106-14 | MRSA | +++ | +++ | +++ | +/− | — | +++ | +++ | +/− | — | — |
∗+++: growing very well; +/−: growing slightly; —: no growth.