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. 2015 Aug 19;2015:764906. doi: 10.1155/2015/764906

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Copyright © 2015 Hyuk-Woo Kwon et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Effects of G-Ro on ATP and serotonin release. (a) Effects of G-Ro on ATP release in thrombin-activated platelets. (b) Effects of G-Ro on serotonin release in thrombin-activated platelets. (c) Effects of G-Ro on ATP release in the presence of A-kinase inhibitor (Rp-8-Br-cAMPS) and G-kinase inhibitor (Rp-8-Br-cGMPS). (d) Effects of G-Ro on serotonin release in the presence of A-kinase inhibitor (Rp-8-Br-cAMPS) and G-kinase inhibitor (Rp-8-Br-cGMPS). Determination of ATP and serotonin release was carried out as described in “Section 2.” The data are expressed as mean ± standard deviation (n = 4). ^∗ p < 0.05 versus the thrombin-stimulated human platelets, ^# p < 0.05 versus the thrombin-stimulated human platelets in the presence of G-Ro (155 μM), and ^† p < 0.05 versus the thrombin-stimulated human platelets in the presence of G-Ro (300 μM).