Fig. 2.
Mean (± SE) CSF proopiomelanocortin (POMC) levels were significantly higher in lean vs. OW/OB subjects and in males vs. females (top left). There were strong negative correlations between CSF POMC and CSF leptin (top right) and between CSF POMC and BMI (bottom left). There was a strong positive correlation between CSF POMC and CSF sOB-R (bottom right).