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Single-channel patch-clamp recordings measuring the effect of the CaMKII inhibitor KN93 on ENaC Po in Xenopus 2F3 cells. A: representative single-channel patch-clamp recordings illustrating inhibition of CaMKII with the pharmacological inhibitor KN93 (0.5 μM) increases the activity of ENaC. B: summary line graph showing the Po of ENaC increases after inhibiting CaMKII with KN93. Values are means ± SE. *P < 0.05.
