Fig. 3.

Knockdown of integrin-β₁ inhibits amiloride-sensitive current in glioma cells. A: current-voltage relationships show significant attenuation of amiloride-sensitive whole cell current after knockdown of integrin-β₁ (n ≥ 6). B: average amiloride-sensitive conductance in D54MG cells. C: current-voltage relationships recorded from U87MG cells transfected with shRNA targeting integrin-β₁. D: average amiloride-sensitive conductance in U87MG cells. **P < 0.01; ***P < 0.001 by ANOVA and Dunnett's post hoc test.