Table 3. Regions showing distant functional connectivity density differences among the MHE, non-HE patients, and healthy controls.
Brain regions | BA | MNI coordinates (mm) | Vol (mm3) | Maximal F value |
---|---|---|---|---|
(x, y, z) | ||||
Left IPL | 40 | −54, −54, 45 | 137 | 10.56 |
Right IPL | 40 | 54, −54, 45 | 112 | 8.65 |
Left cuneus | 18/19 | −3, −84, 21 | 175 | 8.79 |
Right cuneus | 18/19 | 7, −84, 21 | 226 | 8.80 |
Left precuneus | 7 | −27, −78, 36 | 55 | 8.68 |
Right precuneus | 7 | 25, −70, 36 | 137 | 9.20 |
Left thalamus | −18, −36, 6 | 88 | 8.25 | |
Right thalamus | 21, −33, 9 | 78 | 16.44 | |
Left caudate head | −6, 3, 15 | 91 | 7.63 | |
Right caudate head | 6, 15, 13 | 57 | 8.32 | |
Left MTG | 21 | −66, −42, −9 | 64 | 6.06 |
Right MFG | 10 | 39, 51, 6 | 51 | 6.16 |
Medial Frontal Cortex | 9 | 3, 33, 30 | 56 | 7.78 |
MHE = minimal hepatic encephalopathy; non-HE = non hepatic encephalopathy; BA = Brodmann area; MNI = Montreal Neurological Institute; IPL = inferior parietal lobule; MTG = middle temporal gyrus; MFG = middle frontal gyrus. P < 0.05, corrected for multiple comparisons.