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. 2015 Jun 26;54(31):8896–8927. doi: 10.1002/anie.201412070

Figure 12.

Figure 12

Chemical structures of sterically enforced structural α-helix mimetics: A terphenyl (27), two different heterocyclic scaffolds (28 and 29), and a pyrrolopyrimidine (30). The substituents highlighted in gray are designed to mimic the i, i+3/4, and i+7 side chains of an α-helix.