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. 2015 Sep 2;9:310. doi: 10.3389/fnins.2015.00310

Figure 5.

Figure 5

The effects of dopaminergic compounds on cyp19a1b mRNA levels in RGC culture. Quantitative real-time PCR analysis of the cyp19a1b mRNA, normalized to 18s in primary RGC culture after 24 h exposure of different dosages of SKF 38393(A), different dosages of Quinpirole (B), SKF 38393 and/or Flup (C), SKF 38393 and/or SKF 83566 (D), SKF 38393 and/or DOM (E). DMSO was used as a vehicle to dissolve SKF 83566 and DOM, which showed no effects on cyp19a1b mRNA levels in RGC culture (Supplemental Figure 4, P = 0.4153). Data were defined as fold change relative to control, the bars represent the mean + SEM (n = 4), each sample was analyzed in duplicate. a,b-Groups marked by different letters are significantly different (P < 0.05).