Fig. 5.

Schematic of the four overlapping deletion events found during the thermal evolution experiments. a The largest deletion (ECB_00503_large) removes 64 genes and was found in 35 of 115 evolved clones. b The smaller deletion (ECB_00503_small) was found in 9 of 115 clones and removed 38 genes. c An even smaller variant was found in 1 of 115 clones and removed 18 genes. d The hokE_large mutation removed 24 genes and was found in 3 of 115 clones. All variants are described in Tenaillon et al. [5]. In all diagrams, numbers at the 5′ and 3′ end of the schematic represent the base position on the reference genome [35]