Table 4.
Associations between apolipoprotein B and β2-glycoprotein-I (GPI) autoantibodies and carotid intima-media thickness (IMT) in systemic lupus erythematosus (SLE) patients
| SLE patients (n = 302) | P | P adjusted for age and gender | |
|---|---|---|---|
| Apolipoprotein B antibodies | |||
| p45 IgM | −0·05 | n.s. | 0·02 |
| MDA-p45 IgM | −0·08 | n.s. | 0·02 |
| p45 IgG | −0·10 | n.s. | n.s. |
| MDA-p45 IgG | −0·07 | n.s. | n.s. |
| p210 IgM | −0·23 | 0·001 | n.s. |
| MDA-p210 IgM | −0·16 | 0·005 | n.s. |
| p210 IgG | −0·20 | 0·001 | n.s. |
| MDA-p210 IgG | −0·19 | 0·001 | n.s. |
| Apolipoprotein H antibodies | |||
| β2GPI IgM | 0·04 | n.s. | n.s. |
| β2GPI IgG | −0·03 | n.s. | n.s. |
Partial correlations were calculated to determine independent associations between autoantibodies and IMT when controlling for age and sex. Ig = immunoglobulin; MDA = malondialdehyde; n.s. = not significant.