The effect of immunosuppression on chemokine and cytokine levels in the plasma. The concentration (pg/ml) of chemokines and cytokines in plasma were determined using multiplex technology in individual rhesus macaques (RMs) from (a) cohort 1, (b) cohort 2 and (c) cohort 3. Dashed line indicates onset or change in immunosuppressive treatment; total body irradiation (TBI), cyclosporin A (CsA), tacrolimus (TAC), prednisone (pred), anti-thymocyte globulin (ATG), anti-CD3 immunotoxin (CD3-IT) and Janus activated kinase inhibitor (JAK-Inh).