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. 2015 Jun 29;181(3):491–510. doi: 10.1111/cei.12646

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Fig. 8 — The effect of immunosupression the frequency of simian varicella virus (SVV)-specific T cells. Percentage of SVV-specific CD4 and CD8 T cells in peripheral blood mononuclear cells (PBMC) producing interferon (IFN)-γ and/or tumour necrosis factor (TNF)-α was measured by intracellular cytokine staining following stimulation with SVV lysate in individual rhesus macaques (RMs) from (c) cohort 1, (d) cohort 2 and (e) cohort 3. Dashed line indicates onset or change in immunosuppressive treatment; total body irradiation (TBI), cyclosporin A (CsA), tacrolimus (TAC), prednisone (pred), anti-thymocyte globulin (ATG), anti-CD3 immunotoxin (CD3-IT) and Janus activated kinase inhibitor (JAK-Inh).