Table 1. HLA-A*0201-restricted CD8 T cell epitopes.
Antigen | Epitope | Sequence | Subjects* |
---|---|---|---|
Preproinsulin | PPI15-24 | ALWGPDPAAA | 14/14 |
Insulin B chain | InsB10-18 | HLVEALYLV | 10/13 |
Islet-specific glucose-6-phosphatase catalytic subunit-related protein |
IGRP265-273 | VLFGLGFAI | 13/12 |
Islet tyrosine phosphatase | IA-2797-805 | MVWESGCTV | 11/13 |
Glutamic acid decarboxylase 65 | GAD65114-123 | VMNILLQYVV | 11/10 |
Cytomegalovirus pp65 | CMV pp65495-503 | NLVPMVATV | 14/13 |
Epstein-Barr virus BMLF1 | EBV BMLF1280-288 | GLCTLVAML | 13/12 |
Numbers of healthy controls/type 1 diabetes patients studied for each epitope specificity.