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. 2015 Sep 3;10:42. doi: 10.1186/s13024-015-0036-5

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© Wang et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Generation of transgenic TDP-43 pigs. a The plasmid DNA structure for expressing mutant TDP-43 (M337V) under the human ubiquitin promoter in transgenic pigs. F2A is a peptide sequence that can self-cleave to separate TDP-43 from EGFP in cells. b The numbers of embryos used and transgenic TDP-43 pigs produced. c PCR genotype analysis of ear tissues from 15 transgenic TDP-43 pigs. Two non-transgenic pig (Control) ear tissues served as a control

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