Table 2.
Characteristics of patients undergoing hepatectomy for colorectal liver metastases, based on PPC status, in the matched cohort
| PPC (n = 110) | No PPC (n = 110) | P-value | |
|---|---|---|---|
| Time period 2008–2012 a | 72 (65.5) | 72 (65.5) | 1.00 |
| Age (years old)a | 63.0 (56.0–72.0) | 63.0 (56.0–71.2) | 0.921 |
| Male Gender | 67.0 (60.9) | 75 (68.2) | 0.286 |
| Pre-operative haemoglobin (g/l) | 134.0 (122.0–145.5) | 135.0 (123.0–143.0) | 0.281 |
| Pre-operative bilirubin (μmol/l) | 7.0 (5.0–9.0) | 8.0 (6.0–11.7) | 0.241 |
| Pre-operative INR | 0.98 (0.93–1.02) | 0.98 (0.94–1.03) | 0.721 |
| Pre-operative albumin (g/l) | 42.0 (40.0–44.7) | 42.0 (39.0–45.0) | 0.942 |
| Pre-operative creatinine (μmol/l) | 76.0 (63.0–84.7) | 75.0 (62.0–88.0) | 0.445 |
| Pre-operative platelet count (109/l) | 208.0 (174.5–250.0) | 217.0 (188.0–271.5) | 0.035 |
| Clinical risk scorea | |||
| 0 | 8 (7.3) | 8 (7.3) | 1.00 |
| 1 | 32 (29.1) | 32 (29.1) | |
| 2 | 37 (33.6) | 37 (33.6) | |
| 3 | 29 (26.4) | 29 (26.4) | |
| 4 | 4 (2.6) | 4 (2.6) | |
| 5 | 0 (0) | 0 (0) | |
| Pre-operative chemotherapy | 94 (85.5) | 87 (79.1) | 0.217 |
| Major liver resectionb | 69 (63.3) | 67 (60.9) | 0.715 |
| Estimated blood loss (l) | 1.0 (0.5–1.8) | 1.0 (0.5–1.5) | 0.232 |
| Operative time (hours) | 5.1 (4.0–6.1) | 4.5 (3.4–5.9) | 0.057 |
| Intra-operative complication | 5 (4.5) | 9 (8.2) | 0.322 |
| Peri-operative RBC transfusion | 31 (28.2) | 26 (23.9) | 0.465 |
| Major morbidity | 16 (14.5) | 20 (18.2) | 0.429 |
| 90-day mortality | 8 (7.3) | 7 (6.4) | 0.404 |
| Length of stay (days) | 7.0 (6.0–9.0) | 8.0 (6.0–11.0) | 0.100 |
| 30-day re-admission | 1 (0.9) | 5 (4.5) | 0.098 |
| Resection margin status | |||
| R0 | 98 (89.1) | 102 (92.7) | 0.366 |
| R1 | 6 (5.5) | 1 (1.8) | |
| R2 | 1 (0.9) | 0 (0) | |
| Unknownc | 5 (4.5) | 6 (5.5) | |
Values are n (%) or median (inter-quartile range).
a
Factors used for matching.
b
Major liver resection: ≥3 liver segments resected.
c
Margin status could not be identified in the pathology report.
RBC, red blood cells.