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. 2015 Feb 13;144(3):412–421. doi: 10.1111/imm.12385

Figure 4.

Figure 4

Perforin expression in CD8 T cells from peripheral blood mononuclear cells (PBMC) of acute and chronic HIV-infected patients and healthy controls. (a) FACS analysis of perforin expression in CD8 T cells in acute HIV infection (blue), chronic HIV infection (red), and non-infected controls (black) (four different experiments are presented). (b) Statistical analysis of perforin expression in sorted CD8 T cells of acute and chronic HIV-infected patients and healthy controls (average ± SE), bars with different letters differ at < 0·05 (Tukey–Kramer test). (c) Immunofluorescence of CD8 (blue) and perforin (green) in conjugated CD8–CD4 T cells of acute and (d) chronic HIV-infected patients. Each scale bar is 10 μm.